According to a politician, 32 Venezuelan migrants are missing after the boat they were travelling on sank on its way to the island of Curaçao.
The group left a village in the north-western Falcón state on a speedboat on Friday.
According to their relatives, they had not heard from the group since.
It was the third Venezuelan migrant boat to capsize in recent weeks.
Some four million people have fled Venezuela since 2015, according to the United Nations.
A severe years-long economic crisis has resulted in high unemployment and shortages of food and medicine, and hundreds of thousands of people are said to be in need of humanitarian aid in the oil-rich country.
"No-one has been in touch with their families, which makes us fear the worst," said opposition politician Luis Stefanelli, who accused the government of "criminal negligence" for not deploying teams to search for the missing.